How should you combine tramadol with acetaminophen or ibuprofen? – Always follow the directions given on your medicine’s label. As a general guide for adults (aged 18 to 75 years) in acute pain:

Tramadol: 50 to 100mg every 4 to 6 hours up to a maximum of 400mg/day Acetaminophen 2 tablets every 4 to 6 hours up to 5 days. Maximum of 8 tablets per day Ibuprofen: 200mg to 400mg up to 4 times a day. Maximum of 4 doses per day.

Can I take Tylenol with tramadol 50mg?

Descriptions – Tramadol and acetaminophen combination is used to relieve acute pain severe enough to require an opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. When used together, the combination provides better pain relief than either medicine used alone.

• In some cases, you may get relief with lower doses of each medicine.
• Tramadol belongs to the group of medicines called opioid analgesics (narcotics).
• It acts in the central nervous system (CNS) to relieve pain.
• When tramadol is used for a long time, it may become habit-forming (causing mental or physical dependence).

Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to side effects when you suddenly stop taking the medicine. Since this medicine is only used for short-term relief of pain, mental and physical dependence will probably not occur.

Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage. Although rare, use of acetaminophen has been reported to lead to liver transplantation and death, usually at high doses and when multiple acetaminophen-containing products have been used.

This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program. This product is available in the following dosage forms:

Tablet

How much Tylenol do I take with tramadol?

Additional dosage information: –

• Usual dose: 2 tablets orally every 4 to 6 hours as needed for pain Maximum dose: 8 tablets per day Maximum duration: 5 days
• Comments:

• Each tablet contains Tramadol 37.5 mg and Acetaminophen 325 mg. Maximum daily doses are Tramadol: 300 mg per day and Acetaminophen 2600 mg per day.
• Use of more than 1 product at time containing acetaminophen is not recommended.
• Due to the risks of addiction, abuse, and misuse, this drug is reserved for patients who have not been or are not expected to tolerate non-opioid pain medications or who have not obtained or are not expected to obtain analgesia with other pain management treatments.

Use: For the short-term (use should be limited to 5 days or less) management of acute pain, severe enough to require an opioid analgesic and for whom alternative treatments are inadequate.

Is it OK to take 2 50 mg tramadol?

You take two single doses of Tramadol 50 mg capsules at once by mistake, this will generally not be harmful. If pain returns, continue taking Tramadol 50 mg Capsules as usual. If high doses are taken accidentally (e.g. a dose of more than two Tramadol 50 mg Capsules at once), a number of symptoms may occur.

Can you take tramadol 37.5 mg with acetaminophen?

Individualization of Dose – In patients with creatinine clearances of less than 30 mL/min, it is recommended that the dosing interval of Tramadol HCl 37.5 mg/Acetaminophen 325 mg be increased not to exceed 2 tablets every 12 hours. Dose selection for an elderly patient should be cautious, in view of the potential for greater sensitivity to adverse events.

Tramadol Hydrochloride 37.5 mg/Acetaminophen 325 mg tablets are light yellow, coated, capsule-shaped tablets imprinted “O-M” on one side and “650” on the other and are available as follows: Bottles of 28 – NDC 16590-230-28 Bottles of 30 – NDC 16590-230-30 Bottles of 40 – NDC 16590-230-40 Bottles of 50 – NDC 16590-230-50 Bottles of 60 – NDC 16590-230-60 Bottles of 84 – NDC 16590-230-62 Bottles of 90 – NDC 16590-230-90 Bottles of 100 – NDC 16590-230-71 Bottles of 112 – NDC 16590-230-73 Bottles of 120 – NDC 16590-230-72 Bottles of 180 – NDC 16590-230-82 Dispense in a tight container.

Store at 25°C (77°F); excursions permitted to 15 – 30°C (59 – 86°F). Manufactured by: JOLLC Gurabo, Puerto Rico 00778 Distributed by: IVAX PHARMACEUTICALS, INC. Sellersville, PA 18960 Revised June 2011 Relabeling and Repackaging by : STAT Rx USA LLC Gainesville, GA 30501

Can I take 2 Tylenol and 1 tramadol?

How should I take acetaminophen and tramadol? – Follow the directions on your prescription label and read all medication guides. Never use this medicine in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of this medicine.

Never share acetaminophen and tramadol with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law. The maximum amount of acetaminophen and tramadol is 2 tablets per dose, or 8 tablets per day.

Do not take this medicine for longer than 5 days in a row. You may take this medicine with or without food, but take it the same way each time. You should not stop using this medicine suddenly after long-term use. Follow your doctor’s instructions about tapering your dose.

• Store at room temperature away from moisture and heat.
• Eep your medicine in a place where no one can use it improperly.
• Do not keep leftover medication.
• Just one dose can cause death in someone using this medicine accidentally or improperly.
• Ask your pharmacist where to locate a drug take-back disposal program.

If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash. What happens if I miss a dose?

Can I take 2 Extra Strength Tylenol with tramadol?

Interactions between your drugs – No interactions were found between tramadol and Tylenol Extra Strength. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Can I take Tylenol 5 hours after tramadol?

Interactions between your drugs – No interactions were found between tramadol and Tylenol. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

What’s the best pain reliever to take with tramadol?

Taking tramadol with other painkillers – It’s safe to take tramadol with paracetamol, ibuprofen or aspirin (aspirin is only suitable for most people aged 16 and over). Some everyday painkillers that you can buy from pharmacies contain codeine, which is a similar medicine to tramadol.

Can you take Tylenol 8 hours after tramadol?

Interactions between your drugs – No interactions were found between tramadol and Tylenol 8 Hour. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Is 50mg of tramadol strong?

Tramadol 50mg

ME DICATION GUIDE Tramadol hydrochloride ( tram’ a dol hye” droe klor’ ide) Tablets, USP, CIV Tramadol hydrochloride tablets are :

A strong prescription pain medicine that contains an opioid (narcotic) that is used for the management pain in adults, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough or you cannot tolerate them. An opioid pain medicine that can put you at risk for overdose and death. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death.

I mportant information about tramadol hydrochloride tablets:

G et emergency help right away if you take too much tramadol hydrochloride tablets (overdose), When you first start taking tramadol hydrochloride tablets, when your dose is changed, or if you take too much (overdose), serious or life-threatening breathing problems that can lead to death may occur. Taking tramadol hydrochloride tablets with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death. Never give anyone else your tramadol hydrochloride tablets. They could die from taking it. Store tramadol hydrochloride tablets away from children and in a safe place to prevent stealing or abuse. Selling or giving away tramadol hydrochloride tablets is against the law.

Important Information Guiding Use in Pediatric Patients:

Do not give tramadol hydrochloride tablets to a child younger than 12 years of age. Do not give tramadol hydrochloride tablets to a child younger than 18 years of age after surgery to remove the tonsils and/or adenoids. Avoid giving tramadol hydrochloride tablets to children between 12 to 18 years of age who have risk factors for breathing problems such as obstructive sleep apnea, obesity, or underlying lung problems. Do not take tramadol hydrochloride tablets if you have: Severe asthma, trouble breathing, or other lung problems. A bowel blockage or have narrowing of the stomach or intestines. An allergy to tramadol.

Taken a Monoamine Oxidase Inhibitor, MAOI, (medicine used for depression) within the last 14 days. Before taking tramadol hydrochloride tablets, tell your healthcare provider if you have a history of:

head injury, seizures problems urinating abuse of street or prescription drugs, alcohol addiction, or mental health problems. liver, kidney, thyroid problems pancreas or gallbladder problems

Tell your healthcare provider if you are:

pregnant or planning to become pregnant. Prolonged use of tramadol hydrochloride tablets during pregnancy can cause withdrawal symptoms in your newborn baby that could be life- threatening if not recognized and treated. breastfeeding, Not recommended; it may harm your baby. taking prescription or over-the-counter medicines, vitamins, or herbal supplements. Taking tramadol hydrochloride tablets with certain other medicines can cause serious side effects that could lead to death.

When taking tramadol hydrochloride tablets: Do not change your dose. Take tramadol hydrochloride tablets exactly as prescribed by your healthcare provider. Use the lowest dose possible for the shortest time needed. Take your prescribed dose as indicated by your healthcare provider.

The maximum dosage is 1 or 2 tablets every 4 to 6 hours, as needed for pain relief. Do not take more than your prescribed dose and do not take more than 8 tablets per day. If you miss a dose, take your next dose at your usual time. Call your healthcare provider if the dose you are taking does not control your pain.

If you have been taking tramadol hydrochloride tablets regularly, do not stop taking tramadol hydrochloride tablets without talking to your healthcare provider. After you stop taking tramadol hydrochloride tablets, ask your pharmacist how to dispose of any unused tablets.

While taking tramadol hydrochloride tablets DO NOT: Drive or operate heavy machinery, until you know how tramadol hydrochloride tablets affects you. Tramadol hydrochloride tablets can make you sleepy, dizzy, or lightheaded. Drink alcohol or use prescription or over-the-counter medicines that contain alcohol.

Using products containing alcohol during treatment with tramadol hydrochloride tablets may cause you to overdose and die. The possible side effects of tramadol hydrochloride tablets:

constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain. Call your healthcare provider if you have any of these symptoms and they are severe.

Get emergency medical help if you have:

trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue, or throat, extreme drowsiness, light-headedness when changing positions, feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion. These are not all the possible side effects of tramadol hydrochloride tablets. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. For more information go to dailymed.nlm.nih.gov.

Health care professionals should not abruptly discontinue opioids in a patient who is physically dependent. When you and your patient have agreed to taper the dose of opioid analgesic, consider a variety of factors, including the dose of the drug, the duration of treatment, the type of pain being treated, and the physical and psychological attributes of the patient.

No standard opioid tapering schedule exists that is suitable for all patients. Create a patient-specific plan to gradually taper the dose of the opioid and ensure ongoing monitoring and support, as needed, to avoid serious withdrawal symptoms, worsening of the patient’s pain, or psychological distress (For tapering and additional recommendations, see Additional Information for Health Care Professionals).

Patients taking opioid pain medicines long-term should not suddenly stop taking your medicine without first discussing with your health care professional a plan for how to slowly decrease the dose of the opioid and continue to manage your pain. Even when the opioid dose is decreased gradually, you may experience symptoms of withdrawal (See Additional Information for Patients).

If you are taking opioid pain medicines long-term, do not suddenly stop taking your medicine without first discussing with your health care professional a plan for gradually getting off the medicine. Stopping opioids abruptly or reducing the dose too quickly can result in serious problems, including withdrawal symptoms, uncontrolled pain, and thoughts of suicide. Even when the opioid dose is decreased gradually, you may experience symptoms of withdrawal such as:

Restlessness Eye tearing Runny nose Yawning Sweating Chills Muscle aches

Other symptoms also may develop, including:

Irritability Anxiety Difficulty sleeping Backache Joint pain Weakness Abdominal cramp Loss of appetite Nausea Vomiting Diarrhea Increased blood pressure or heart rate Increased breathing rate

Contact your health care professional if you experience increased pain, withdrawal symptoms, changes in your mood, or thoughts of suicide. Also contact them if you have any questions or concerns.

Additional Information for Health Care Professionals

Do not abruptly discontinue opioid analgesics in patients physically dependent on opioids. Counsel patients not to discontinue their opioids without first discussing the need for a gradual tapering regimen. Abrupt or inappropriately rapid discontinuation of opioids in patients who are physically dependent has been associated with serious withdrawal symptoms, uncontrolled pain, and suicide. Abrupt or rapid discontinuation has also been associated with attempts to find other sources of opioid analgesics, which may be confused with drug-seeking for abuse. Patients may also attempt to treat their pain or withdrawal symptoms with illicit opioids, such as heroin, and other substances. It is important to ensure ongoing care of the patient and to agree on an appropriate tapering schedule and follow-up plan so that patient and provider goals and expectations are clear and realistic. When deciding how to discontinue or decrease therapy in an opioid-dependent patient, consider a variety of factors, including the dose of the opioid analgesic the patient has been taking, the duration of treatment, the type of pain being treated, and the physical and psychological attributes of the patient. There are no standard opioid tapering schedules that are suitable for all patients. A patient-specific plan should be used to taper the dose of the opioid gradually. In general, for patients who are physically dependent on opioids, taper by an increment of no more than 10 percent to 25 percent every 2 to 4 weeks. It may be necessary to provide the patient with lower dosage strengths to accomplish a successful taper. If the patient is experiencing increased pain or serious withdrawal symptoms, it may be necessary to pause the taper for a period of time, raise the opioid analgesic to the previous dose, and then once stable, proceed with a more gradual taper. When managing patients taking opioid analgesics, particularly those who have been treated for a long duration and/or with high doses for chronic pain, ensure that a multimodal approach to pain management, including mental health support (if needed), is in place prior to initiating an opioid analgesic taper. A multimodal approach to pain management may optimize the treatment of chronic pain, as well as assist with the successful tapering of the opioid analgesic. Patients who have been taking opioids for shorter time periods may tolerate a more rapid taper. Frequent follow-up with patients is important. Reassess the patient regularly to manage pain and withdrawal symptoms that emerge. Common withdrawal symptoms include:

Restlessness Lacrimation Rhinorrhea Yawning Perspiration Chills Myalgia Mydriasis

Other symptoms also may develop, including:

Irritability Anxiety Insomnia Backache Joint pain Weakness Abdominal cramps Anorexia Nausea Vomiting Diarrhea Increased blood pressure or heart rate Increased respiratory rate

Patients should also be monitored for suicidal thoughts, use of other substances, or any changes in mood. When opioid analgesics are being discontinued due to a suspected substance use disorder, evaluate and treat the patient, or refer him/her for evaluation and treatment of the substance use disorder. Treatment should include evidence-based approaches such as medication assisted treatment of opioid use disorder. Complex patients with comorbid pain and substance use disorders may benefit from referral to a specialist.

This Medication Guide has been approved by the U.S. Food and Drug Administration. Revised: 1/2021 : Tramadol 50mg

Is 50mg of tramadol a lot?

How Much Tramadol Is Too Much? – Doctors recommend that patients take no more than 50 mg of short-acting tramadol every six hours as needed, or 100 mg of long-acting tramadol per day when starting out. This amount may be increased as tolerances do. However, the max dose of the drug is 300 mg a day for the short-acting formulation and 400 mg a day for the long-acting formulation.

Can I take 2 Tylenol 500 with tramadol?

Yes, it is safe for most people to take tramadol with acetaminophen, ibuprofen, or aspirin if they are old enough (aspirin is not recommended for children less than 16 years and tramadol should not be taken by children under the age of 12). Taking tramadol in combination with other medicines can provide better pain relief than just taking one pain-relieving medicine by itself,

• The combination of tramadol and acetaminophen may be used to relieve acute pain that is severe enough to require an opioid medication, but there are many reasons why you would not want to give an opioid medication.
• When tramadol and acetaminophen are used together, the combination provides better pain relief than either medicine used alone.

The combination of tramadol and ibuprofen or tramadol and aspirin (in people over the age of 16) also provides better pain relief than either one used alone. Tramadol should not be taken at the same time as codeine, because both medications are structurally similar, and the combination can result in increased drowsiness.

What if tramadol is not working for pain?

Proper Use – Drug information provided by: Merative, Micromedex ® Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

1. It is very important that you understand the rules of the Opioid Analgesic REMS program to prevent addiction, abuse, and misuse of acetaminophen and codeine combination.
2. This medicine should come with a Medication Guide.
3. Read and follow the instructions carefully.
4. Read it again each time you refill your prescription in case there is new information.

Ask your doctor if you have any questions. If you think that this medicine is not working as well after you have been taking it for a few weeks, do not increase the dose. Instead, check with your doctor. Swallow the extended-release capsule, extended-release tablet, and tablet whole with liquids.

Is Tylenol better than tramadol?

Tramadol is considered an opioid, acts on the central nervous system, and can be habit-forming. It is considered a stronger pain medication than acetaminophen and treats moderate to moderately severe pain. Tramadol can only be taken when prescribed (specially ordered by a doctor).

What happens if I take 2 tramadol instead of 1?

If you take too much – It’s important not to take more than your prescribed dose, even if you think it’s not enough to relieve your pain. Speak to your doctor first if you think you need a different dose. Taking too much tramadol can be dangerous. If you’ve taken too much, you may feel very sleepy, sick or dizzy.

• You may also find it difficult to breathe.
• In serious cases you can become unconscious and may need emergency treatment in hospital.
• The amount of tramadol that can lead to an overdose is different for everyone.
• If you’ve taken 1 extra dose, check the information that comes with the medicine packaging or ask your pharmacist or doctor for advice.

Generally, you are unlikely to get any symptoms from 1 extra dose and you can take your next dose as usual.

How close together can you take 50 mg tramadol?

Dosage for moderate to severe pain – Adult dosage (ages 18–64 years) Immediate-release tablet:

• Typical daily dosage: Total daily dosage may be increased by 50 mg as tolerated every 3 days to reach 200 mg/day (50 mg 4 times a day).
• Maintenance dosage: 50–100 mg every 4–6 hours as needed.
• Maximum dosage: 400 mg per day.

Extended-release tablet:

• If you’re not currently taking tramadol immediate-release tablets:
  • Typical starting dosage: 100 mg once per day.
  • Dosage increases: Your doctor may slowly increase your dose by 100 mg every 5 days.
  • Maximum dosage: 300 mg per day.
  • If you’re currently taking tramadol immediate-release tablets:
    • Typical starting dosage: Your doctor will determine your new dosage based on your previous immediate-release dosage.
    • Maximum dosage: 300 mg per day.

Child dosage (ages 0–17 years) Immediate-release tablet:

• Child dosage (age 17 years):
  • Typical daily dosage: Total daily dosage may be increased by 50 mg as tolerated every 3 days to reach 200 mg/day (50 mg 4 times a day).
  • Maintenance dosage: 50–100 mg every 4–6 hours as needed.
  • Maximum dosage: 400 mg per day.
  • Child dosage (ages 0–16 years):
    • It’s not known if this form of tramadol is safe and effective for children younger than 17 years old. It should not be used in children of this age group.

Extended-release tablet:

• Child dosage (ages 0–17 years):
  • It’s not known if these forms of tramadol are safe and effective for children. They should not be used in people younger than 18 years.

Senior dosage (ages 65 years and older)

• The liver and kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.
• Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.
• If you’re older than 75 years, your maximum dosage of the immediate-release tablet is 300 mg per day.

Is tramadol a muscle relaxer or painkiller?

No, Tramadol is not an anti-inflammatory drug or muscle relaxer. It’s a synthetic opioid that relieves pain. Because it’s not an anti-inflammatory drug, it likely won’t reduce any swelling you have when taken alone. But, tramadol is often combined with a nonsteroidal anti-inflammatory drug (NSAID) or acetaminophen to relieve moderate to severe pain.

It works like a traditional opioid, blocking pain signals from opioid receptors in the brain and nervous system. Unlike other opioids, tramadol also acts like some antidepressants, reducing pain by keeping pain messages from traveling between brain cells.

Brand names of tramadol include:

ConZip Qdolo Ultram Ultram ER

It’s also available in generic form. Combined medications like Ultracet (tramadol and acetaminophen) are also approved. Sometimes it is prescribed along with an NSAID, like ibuprofen, When used alone, tramadol doesn’t have the same side effects that NSAIDs can have, such as kidney problems or bleeding in the stomach or intestines.

Sleepiness Dizziness Nausea Constipation Sweating

As with other opioids, Tramadol can be abused and misused, so preventive measures against addiction and abuse should be taken. Tramadol and other opioids are safest when taken only as prescribed.

Can you take tramadol on an empty stomach?

pronounced as (tra’ ma dole) FDA Drug Safety Communication:

As part of its ongoing efforts to address the nation’s opioid crisis, FDA is requiring several updates to the prescribing information of opioid pain medicines. The changes are being made to provide additional guidance for safe use of these drugs while also recognizing the important benefits when used appropriately. The changes apply to both immediate-release (IR) and extended-release/long-acting preparations (ER/LA).Updates to the IR opioids state that these drugs should not be used for an extended period unless the pain remains severe enough to require an opioid pain medicine and alternative treatment options are insufficient, and that many acute pain conditions treated in the outpatient setting require no more than a few days of an opioid pain medicine.Updates to the ER/LA opioids recommend that these drugs be reserved for severe and persistent pain requiring an extended period of treatment with a daily opioid pain medicine and for which alternative treatment options are inadequate.A new warning is being added about opioid-induced hyperalgesia (OIH) for both IR and ER/LA opioid pain medicines. This includes information describing the symptoms that differentiate OIH from opioid tolerance and withdrawal.Information in the boxed warning for all IR and ER/LA opioid pain medicines will be updated and reordered to elevate the importance of warnings concerning life-threatening respiratory depression, and risks associated with using opioid pain medicines in conjunction with benzodiazepines or other medicines that depress the central nervous system (CNS).Other changes will also be required in various other sections of the prescribing information to educate clinicians, patients, and caregivers about the risks of these drugs.

Tramadol may be habit forming, especially with prolonged use. Take tramadol exactly as directed. Do not take more of it, take it more often, or take it in a different way than directed by your doctor. While taking tramadol, discuss with your health care provider your pain treatment goals, length of treatment, and other ways to manage your pain.

Tell your doctor if you or anyone in your family drinks or has ever drunk large amounts of alcohol, uses or has ever used street drugs, or has overused prescription medications, or has had an overdose or if you have or have ever had depression or another mental illness. There is a greater risk that you will overuse tramadol if you have or have ever had any of these conditions.

Talk to your health care provider immediately and ask for guidance if you think that you have an opioid addiction or call the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-HELP. Tramadol may cause serious or life-threatening breathing problems, especially during the first 24 to 72 hours of your treatment and any time your dose is increased.

Your doctor will monitor you carefully during your treatment. Tell your doctor if you have or have ever had slowed breathing, asthma, or lung disease such as chronic obstructive pulmonary disease (COPD; a group of diseases that affect the lungs and airways). Your doctor will probably tell you not to take tramadol.

Also tell your doctor if you have or have ever had a head injury, brain tumor, or any condition that increases the amount of pressure in your brain. The risk that you will develop breathing problems may be higher if you are an older adult or are weak or malnourished due to disease.

If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: slowed breathing, long pauses between breaths, or shortness of breath. When tramadol was used in children, serious and life-threatening breathing problems such as slow or difficulty breathing and deaths were reported.

Tramadol should never be used to treat pain in children younger than 12 years of age or to relieve pain after surgery to remove the tonsils and/or adenoids in children younger than 18 years of age. Tramadol should also not be used in used in children 12 to 18 years of age who are obese or who have a neuromuscular disease (disease that affects the nerves that control voluntary muscles), a lung disease, or obstructive sleep apnea (condition in which the airway becomes blocked or narrow and breathing stops for short periods during sleep) as these conditions may increase their risk of breathing problems.

• Taking certain other medications during your treatment with tramadol may increase the risk that you will experience breathing problems or other serious, life threatening breathing problems, sedation, or coma.
• Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take.

Your doctor may need to change the dosages of your medications and will monitor you carefully. If you take tramadol with other medications and you develop any of the following symptoms, call your doctor immediately or seek emergency medical care: unusual dizziness, lightheadedness, extreme sleepiness, slowed or difficult breathing, or unresponsiveness.

1. Be sure that your caregiver or family members know which symptoms may be serious so they can call the doctor or emergency medical care if you are unable to seek treatment on your own.
2. Drinking alcohol, taking prescription or nonprescription medications that contain alcohol, or using street drugs during your treatment with tramadol increases the risk that you will experience these serious, life-threatening side effects.

Do not drink alcohol, take prescription or nonprescription medications that contain alcohol, or use street drugs during your treatment. Tell your doctor if you are pregnant or plan to become pregnant. If you take tramadol regularly during your pregnancy, your baby may experience life-threatening withdrawal symptoms after birth.

1. Tell your baby’s doctor right away if your baby experiences any of the following symptoms: irritability, hyperactivity, abnormal sleep, high-pitched cry, uncontrollable shaking of a part of the body, vomiting, diarrhea, or failure to gain weight.
2. If you are taking the tramadol extended-release tablet or capsule, swallow them whole; do not chew, break, divide, crush, or dissolve them.

If you swallow broken, chewed, crushed, or dissolved extended-release preparations, you may receive too much tramadol at once instead and this may cause serious problems, including overdose and death. Do not allow anyone else to take your medication. Tramadol may harm or cause death to other people who take your medication, especially children.

1. Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with tramadol and each time you refill your prescription.
2. Read the information carefully and ask your doctor or pharmacist if you have any questions.
3. You can also visit the Food and Drug Administration (FDA) website ( http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm ) or the manufacturer’s website to obtain the Medication Guide.

Tramadol is used to relieve moderate to moderately severe pain in adults and children 12 years of age or older. Tramadol extended-release tablets and capsules are only used by people who are expected to need medication to relieve pain around-the-clock.

1. Tramadol is in a class of medications called opiate (narcotic) analgesics.
2. It works by changing the way the brain and nervous system respond to pain.
3. Tramadol comes as a tablet, a solution (liquid), an extended-release (long-acting) tablet, and an extended-release (long-acting) capsule to take by mouth.

The regular tablet and solution are taken usually with or without food every 4 to 6 hours as needed. The extended-release tablet and extended-release capsule should be taken once a day. Take the extended-release tablet and the extended-release capsule at about the same time of day every day.

• If you are taking the extended-release tablet or extended-release capsule, you should take it consistently, either always with or always without food.
• Take tramadol exactly as directed.
• Do not take more medication as a single dose or take more doses per day than prescribed by your doctor.
• Taking more tramadol than prescribed by your doctor or in a way that is not recommended may cause serious side effects or death.

Your doctor may start you on a low dose of tramadol and gradually increase the amount of medication you take, not more often than every 3 days if you are taking the solution or regular tablets or every 5 days if you are taking the extended-release tablets or extended-release capsules.

If you are taking the solution, use an oral syringe or measuring spoon or cup to measure the correct amount of liquid needed for each dose. Do not use a regular household spoon to measure your dose. Ask your doctor or pharmacist if you need help getting or using a measuring device, Do not stop taking tramadol without talking to your doctor.

Your doctor will probably decrease your dose gradually. If you suddenly stop taking tramadol, you may experience withdrawal symptoms such as nervousness; panic; sweating; difficulty falling asleep or staying asleep; runny nose, sneezing, or cough; pain; hair standing on end; chills; nausea; uncontrollable shaking of a part of your body; diarrhea; or rarely, hallucinations (seeing things or hearing voices that do not exist).

What’s the best pain reliever to take with tramadol?

Taking tramadol with other painkillers – It’s safe to take tramadol with paracetamol, ibuprofen or aspirin (aspirin is only suitable for most people aged 16 and over). Some everyday painkillers that you can buy from pharmacies contain codeine, which is a similar medicine to tramadol.

Is tramadol stronger than extra strength Tylenol?

Tramadol is considered an opioid, acts on the central nervous system, and can be habit-forming. It is considered a stronger pain medication than acetaminophen and treats moderate to moderately severe pain.